2.6% sought medical, psychiatric, or psychological assistance following their most challenging experience.
This study examines the prevalence and factors associated with challenging, difficult, or distressing experiences using classic psychedelics in the US adult population.
8.9% experienced functional impairment lasting more than one day due to such experiences.
2.6% sought medical, psychiatric, or psychological assistance following their most challenging experience.
Additionally, three set and setting variables (negative mindset, no psychological support, major life event prior to experience) and co-use of lithium and other mood stabilizers were associated with overall risk of harm.
These findings align with previous research and offer insights to enhance harm reduction strategies and guide future experimental studies.
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