Media Education and Research Links

Peer-reviewed research studies and clinical trials

A suicide attempt following psilocybin ingestion in a patient with no prior psychiatric history

The possibility of an increased risk of suicidality with psilocybin use is a serious outcome measure that requires further study

Psilocybin and Magic Mushrooms: Patterns of Abuse and Consequences of Recreational Misuse

There are also reports on more severe effects, namely persistent psychosis and myocardial infarction.

Reviewing the Potential of Psychedelics for the Treatment of PTSD

The psychological condition of many PTSD patients is unstable, and they are particularly vulnerable to increases in anxiety when...

Therapeutic guidelines: dangers and contra-indications in therapeutic applications of hallucinogens

Ill-conceived hallucinogen experimentation may induce unstable affect and even precipitate psychotic breaks

Prevalence and associations of challenging, difficult or distressing experiences using classic psychedelics

Approximately one in twenty (4.6 %) reported severely impaired ability to function and roughly one in ten (8.9 %) reported impairment...

Abnormal visual experiences in individuals with histories of hallucinogen use

Very little is known about Hallucinogen Persisting Perception Disorder and related visual abnormalities in hallucinogen users

Evaluating the risk of psilocybin for the treatment of bipolar depression

Despite psilocybin's apparent effectiveness in depression, people with bipolar have been excluded from all modern trials

Psychedelic integration challenges: Participant experiences after a psilocybin truffle retreat in the Netherlands

Emotional volatility (including anxiety, depression and hypomania) were reported in the days and weeks following a psychedelic experience

Challenging experiences after ingesting psilocybin mushrooms

Of the respondents, 2.6% behaved in a physically aggressive or violent manner and 2.7% received medical help

Self-treatment Findings from the Global Drug Survey 2020

Outcomes were generally favorable, but negative effects appeared more frequent than in clinical settings

Trial of investigational COMP360 psilocybin therapy

TESAEs included suicidal behavior, intentional self-injury, and suicidal ideation

Prevalence of distressing experiences using psychedelics

2.6 % reported seeking medical, psychiatric, or psychological assistance in the days or weeks following use